Epac2a-null mice exhibit obesity-prone nature more susceptible to leptin resistance

BACKGROUND: The exchange protein directly activated by cAMP (Epac), which is primarily involved in cAMP signaling, has been known to be essential for controlling body energy metabolism. Epac has two isoforms: Epac1 and Epac2. The function of Epac1 on obesity was unveiled using Epac1 knockout (KO) mi...

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Detalles Bibliográficos
Autores principales: Hwang, M, Go, Y, Park, J-H, Shin, S-K, Song, S E, Oh, B-C, Im, S-S, Hwang, I, Jeon, Y H, Lee, I-K, Seino, S, Song, D-K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309344/
https://www.ncbi.nlm.nih.gov/pubmed/27867203
http://dx.doi.org/10.1038/ijo.2016.208

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