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The Autophagy Level Is Increased in the Synovial Tissues of Patients with Active Rheumatoid Arthritis and Is Correlated with Disease Severity

Rheumatoid arthritis (RA) is a complex and not fully understood autoimmune disease associated with multijoint damage. The main effector cells, the synovial fibroblasts, are apoptosis resistant and hyperplastic which indicate that autophagy level is high in synovial tissue. Real-time PCR, immunocytoc...

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Detalles Bibliográficos
Autores principales: Zhu, Li, Wang, Huaizhou, Wu, Yu, He, Zhengwen, Qin, Yanghua, Shen, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309404/
https://www.ncbi.nlm.nih.gov/pubmed/28255205
http://dx.doi.org/10.1155/2017/7623145