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Inactivation of GIRK channels weakens the pre‐ and postsynaptic inhibitory activity in dorsal raphe neurons

The serotonergic tone of the dorsal raphe (DR) is regulated by 5‐HT (1A) receptors, which negatively control serotonergic activity via the activation of G protein‐coupled inwardly rectifying K(+) (GIRK) channels. In addition, DR activity is modulated by local GABAergic transmission, which is believe...

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Detalles Bibliográficos
Autores principales: Llamosas, Nerea, Ugedo, Luisa, Torrecilla, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309581/
https://www.ncbi.nlm.nih.gov/pubmed/28196855
http://dx.doi.org/10.14814/phy2.13141