Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells

Schwann cells (SCs) generate the myelin wrapping of peripheral nerve axons and are promising candidates for cell therapy. However, to date a renewable source of SCs is lacking. In this study, we show the conversion of skin fibroblasts into induced Schwann cells (iSCs) by driving the expression of tw...

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Detalles Bibliográficos
Autores principales: Mazzara, Pietro Giuseppe, Massimino, Luca, Pellegatta, Marta, Ronchi, Giulia, Ricca, Alessandra, Iannielli, Angelo, Giannelli, Serena Gea, Cursi, Marco, Cancellieri, Cinzia, Sessa, Alessandro, Del Carro, Ubaldo, Quattrini, Angelo, Geuna, Stefano, Gritti, Angela, Taveggia, Carla, Broccoli, Vania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309703/
https://www.ncbi.nlm.nih.gov/pubmed/28169300
http://dx.doi.org/10.1038/ncomms14088

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