CRISPR–Cas9-targeted fragmentation and selective sequencing enable massively parallel microsatellite analysis

Microsatellites are multi-allelic and composed of short tandem repeats (STRs) with individual motifs composed of mononucleotides, dinucleotides or higher including hexamers. Next-generation sequencing approaches and other STR assays rely on a limited number of PCR amplicons, typically in the tens. H...

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Detalles Bibliográficos
Autores principales: Shin, GiWon, Grimes, Susan M., Lee, HoJoon, Lau, Billy T., Xia, Li C., Ji, Hanlee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309709/
https://www.ncbi.nlm.nih.gov/pubmed/28169275
http://dx.doi.org/10.1038/ncomms14291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309709/
https://www.ncbi.nlm.nih.gov/pubmed/28169275
http://dx.doi.org/10.1038/ncomms14291

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