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Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma
The intimate anatomical relationship of the facial nerve to the parotid parenchyma has a significant influence on the presenting signs and symptoms, diagnosis and treatment of parotid neoplasms. However, to our knowledge, hyperactivity of this nerve, presenting as facial spasm, has never been descri...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309717/ https://www.ncbi.nlm.nih.gov/pubmed/28246588 http://dx.doi.org/10.5306/wjco.v8.i1.86 |
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author | Machado, Rosalie A Moubayed, Sami P Khorsandi, Azita Hernandez-Prera, Juan C Urken, Mark L |
author_facet | Machado, Rosalie A Moubayed, Sami P Khorsandi, Azita Hernandez-Prera, Juan C Urken, Mark L |
author_sort | Machado, Rosalie A |
collection | PubMed |
description | The intimate anatomical relationship of the facial nerve to the parotid parenchyma has a significant influence on the presenting signs and symptoms, diagnosis and treatment of parotid neoplasms. However, to our knowledge, hyperactivity of this nerve, presenting as facial spasm, has never been described as the presenting sign or symptom of a parotid malignancy. We report a case of carcinoma arising in a recurrent pleomorphic adenoma of the left parotid gland (i.e., carcinoma ex pleomorphic adenoma) that presented with hemifacial spasms. We outline the differential diagnosis of hemifacial spasm as well as a proposed pathophysiology. Facial paralysis, lymph node enlargement, skin involvement, and pain have all been associated with parotid malignancies. To date the development of facial spasm has not been reported with parotid malignancies. The most common etiologies for hemifacial spasm are vascular compression of the ipsilateral facial nerve at the cerebellopontine angle (termed primary or idiopathic) (62%), hereditary (2%), secondary to Bell’s palsy or facial nerve injury (17%), and hemifacial spasm mimickers (psychogenic, tics, dystonia, myoclonus, myokymia, myorthythmia, and hemimasticatory spasm) (17%). Hemifacial spasm has not been reported in association with a malignant parotid tumor but must be considered in the differential diagnosis of this presenting symptom. |
format | Online Article Text |
id | pubmed-5309717 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-53097172017-02-28 Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma Machado, Rosalie A Moubayed, Sami P Khorsandi, Azita Hernandez-Prera, Juan C Urken, Mark L World J Clin Oncol Case Report The intimate anatomical relationship of the facial nerve to the parotid parenchyma has a significant influence on the presenting signs and symptoms, diagnosis and treatment of parotid neoplasms. However, to our knowledge, hyperactivity of this nerve, presenting as facial spasm, has never been described as the presenting sign or symptom of a parotid malignancy. We report a case of carcinoma arising in a recurrent pleomorphic adenoma of the left parotid gland (i.e., carcinoma ex pleomorphic adenoma) that presented with hemifacial spasms. We outline the differential diagnosis of hemifacial spasm as well as a proposed pathophysiology. Facial paralysis, lymph node enlargement, skin involvement, and pain have all been associated with parotid malignancies. To date the development of facial spasm has not been reported with parotid malignancies. The most common etiologies for hemifacial spasm are vascular compression of the ipsilateral facial nerve at the cerebellopontine angle (termed primary or idiopathic) (62%), hereditary (2%), secondary to Bell’s palsy or facial nerve injury (17%), and hemifacial spasm mimickers (psychogenic, tics, dystonia, myoclonus, myokymia, myorthythmia, and hemimasticatory spasm) (17%). Hemifacial spasm has not been reported in association with a malignant parotid tumor but must be considered in the differential diagnosis of this presenting symptom. Baishideng Publishing Group Inc 2017-02-10 2017-02-10 /pmc/articles/PMC5309717/ /pubmed/28246588 http://dx.doi.org/10.5306/wjco.v8.i1.86 Text en ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Case Report Machado, Rosalie A Moubayed, Sami P Khorsandi, Azita Hernandez-Prera, Juan C Urken, Mark L Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma |
title | Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma |
title_full | Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma |
title_fullStr | Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma |
title_full_unstemmed | Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma |
title_short | Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma |
title_sort | intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309717/ https://www.ncbi.nlm.nih.gov/pubmed/28246588 http://dx.doi.org/10.5306/wjco.v8.i1.86 |
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