Recombinant vacuolar iron transporter family homologue PfVIT from human malaria-causing Plasmodium falciparum is a Fe(2+)/H(+)exchanger

Vacuolar iron transporters (VITs) are a poorly understood family of integral membrane proteins that can function in iron homeostasis via sequestration of labile Fe(2+) into vacuolar compartments. Here we report on the heterologous overexpression and purification of PfVIT, a vacuolar iron transporter...

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Detalles Bibliográficos
Autores principales: Labarbuta, Paola, Duckett, Katie, Botting, Catherine H., Chahrour, Osama, Malone, John, Dalton, John P., Law, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309874/
https://www.ncbi.nlm.nih.gov/pubmed/28198449
http://dx.doi.org/10.1038/srep42850

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