Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression

Local interactions between cancer cells and stroma can produce systemic effects on distant organs to govern cancer progression. Here we show that IGF2 secreted by inhibitor of differentiation (Id1)-overexpressing oesophageal cancer cells instigates VEGFR1-positive bone marrow cells in the tumour mac...

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Detalles Bibliográficos
Autores principales: Xu, Wen Wen, Li, Bin, Guan, Xin Yuan, Chung, Sookja K., Wang, Yang, Yip, Yim Ling, Law, Simon Y. K., Chan, Kin Tak, Lee, Nikki P. Y., Chan, Kwok Wah, Xu, Li Yan, Li, En Min, Tsao, Sai Wah, He, Qing-Yu, Cheung, Annie L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309924/
https://www.ncbi.nlm.nih.gov/pubmed/28186102
http://dx.doi.org/10.1038/ncomms14399

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