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DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

BACKGROUND: Lung disease progression is variable among cystic fibrosis (CF) patients and depends on DNA mutations in the CFTR gene, polymorphic variations in disease modifier genes, and environmental exposure. The contribution of genetic factors has been extensively investigated, whereas the mechani...

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Detalles Bibliográficos
Autores principales:	Magalhães, Milena, Rivals, Isabelle, Claustres, Mireille, Varilh, Jessica, Thomasset, Mélodie, Bergougnoux, Anne, Mely, Laurent, Leroy, Sylvie, Corvol, Harriet, Guillot, Loïc, Murris, Marlène, Beyne, Emmanuelle, Caimmi, Davide, Vachier, Isabelle, Chiron, Raphaël, De Sario, Albertina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310067/ https://www.ncbi.nlm.nih.gov/pubmed/28289476 http://dx.doi.org/10.1186/s13148-016-0300-8

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