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Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI

BACKGROUND: Magnesium alloys have recently been rediscovered as biodegradable implants in musculoskeletal surgery. This study is an ex-vivo trial to evaluate the imaging characteristics of magnesium implants in different imaging modalities as compared to conventional metallic implants. METHODS: A CE...

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Autores principales: Sonnow, Lena, Könneker, Sören, Vogt, Peter M., Wacker, Frank, von Falck, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310087/
https://www.ncbi.nlm.nih.gov/pubmed/28196474
http://dx.doi.org/10.1186/s12880-017-0187-7
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author Sonnow, Lena
Könneker, Sören
Vogt, Peter M.
Wacker, Frank
von Falck, Christian
author_facet Sonnow, Lena
Könneker, Sören
Vogt, Peter M.
Wacker, Frank
von Falck, Christian
author_sort Sonnow, Lena
collection PubMed
description BACKGROUND: Magnesium alloys have recently been rediscovered as biodegradable implants in musculoskeletal surgery. This study is an ex-vivo trial to evaluate the imaging characteristics of magnesium implants in different imaging modalities as compared to conventional metallic implants. METHODS: A CE-approved magnesium Herbert screw (MAGNEZIX®) and a titanium screw of the same dimensions (3.2x20 mm) were imaged using different modalities: digital radiography (DX), multidetector computed tomography (MDCT), high resolution flat panel CT (FPCT) and magnetic resonance imaging (MRI). The screws were scanned in vitro and after implantation in a fresh chicken tibia in order to simulate surrounding bone and soft tissue. The images were quantitatively evaluated with respect to the overall image quality and the extent and intensity of artifacts. RESULTS: In all modalities, the artifacts generated by the magnesium screw had a lesser extent and were less severe as compared to the titanium screw (mean difference of artifact size of solo scanned screws in DX: 0.7 mm, MDCT: 6.2 mm, FPCT: 5.9 mm and MRI: 4.73 mm; p < 0.05). In MDCT and FPCT multiplanar reformations and 3D reconstructions were superior as compared with the titanium screw and the metal-bone interface after implanting the screws in chicken cadavers was more clearly depicted. While the artifacts of the titanium screw could be effectively reduced using metal-artifact reduction sequences in MRI (WARP, mean reduction of 2.5 mm, p < 0.05), there was no significant difference for the magnesium screw. CONCLUSIONS: Magnesium implants generate significantly less artifacts in common imaging modalities (DX, MDCT, FPCT and MRI) as compared with conventional titanium implants and therefore may facilitate post-operative follow-up. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12880-017-0187-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-53100872017-03-13 Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI Sonnow, Lena Könneker, Sören Vogt, Peter M. Wacker, Frank von Falck, Christian BMC Med Imaging Research Article BACKGROUND: Magnesium alloys have recently been rediscovered as biodegradable implants in musculoskeletal surgery. This study is an ex-vivo trial to evaluate the imaging characteristics of magnesium implants in different imaging modalities as compared to conventional metallic implants. METHODS: A CE-approved magnesium Herbert screw (MAGNEZIX®) and a titanium screw of the same dimensions (3.2x20 mm) were imaged using different modalities: digital radiography (DX), multidetector computed tomography (MDCT), high resolution flat panel CT (FPCT) and magnetic resonance imaging (MRI). The screws were scanned in vitro and after implantation in a fresh chicken tibia in order to simulate surrounding bone and soft tissue. The images were quantitatively evaluated with respect to the overall image quality and the extent and intensity of artifacts. RESULTS: In all modalities, the artifacts generated by the magnesium screw had a lesser extent and were less severe as compared to the titanium screw (mean difference of artifact size of solo scanned screws in DX: 0.7 mm, MDCT: 6.2 mm, FPCT: 5.9 mm and MRI: 4.73 mm; p < 0.05). In MDCT and FPCT multiplanar reformations and 3D reconstructions were superior as compared with the titanium screw and the metal-bone interface after implanting the screws in chicken cadavers was more clearly depicted. While the artifacts of the titanium screw could be effectively reduced using metal-artifact reduction sequences in MRI (WARP, mean reduction of 2.5 mm, p < 0.05), there was no significant difference for the magnesium screw. CONCLUSIONS: Magnesium implants generate significantly less artifacts in common imaging modalities (DX, MDCT, FPCT and MRI) as compared with conventional titanium implants and therefore may facilitate post-operative follow-up. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12880-017-0187-7) contains supplementary material, which is available to authorized users. BioMed Central 2017-02-14 /pmc/articles/PMC5310087/ /pubmed/28196474 http://dx.doi.org/10.1186/s12880-017-0187-7 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Sonnow, Lena
Könneker, Sören
Vogt, Peter M.
Wacker, Frank
von Falck, Christian
Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI
title Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI
title_full Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI
title_fullStr Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI
title_full_unstemmed Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI
title_short Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI
title_sort biodegradable magnesium herbert screw – image quality and artifacts with radiography, ct and mri
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310087/
https://www.ncbi.nlm.nih.gov/pubmed/28196474
http://dx.doi.org/10.1186/s12880-017-0187-7
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