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HMGB1/anti-HMGB1 antibodies define a molecular signature of early stages of HIV-Associated Neurocognitive Disorders (HAND)

BACKGROUND: HIV-associated neurocognitive disorders (HAND) persist in the post-HAART era, characterized by asymptomatic neurocognitive impairment (ANI) and mild neurocognitive disorders (MND). High mobility group box 1 (HMGB1) is a non-histone chromosomal protein widely expressed in the nucleus of a...

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Detalles Bibliográficos
Autores principales: Gougeon, Marie-Lise, Poirier-Beaudouin, Béatrice, Durant, Jacques, Lebrun-Frenay, Christine, Saïdi, Héla, Seffer, Valérie, Ticchioni, Michel, Chanalet, Stephane, Carsenti, Helene, Harvey-Langton, Alexandra, Laffon, Muriel, Cottalorda, Jacqueline, Pradier, Christian, Dellamonica, Pierre, Vassallo, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310155/
https://www.ncbi.nlm.nih.gov/pubmed/28224137
http://dx.doi.org/10.1016/j.heliyon.2017.e00245