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Systematic assessment of multi-gene predictors of pan-cancer cell line sensitivity to drugs exploiting gene expression data

Background: Selected gene mutations are routinely used to guide the selection of cancer drugs for a given patient tumour. Large pharmacogenomic data sets, such as those by Genomics of Drug Sensitivity in Cancer (GDSC) consortium, were introduced to discover more of these single-gene markers of drug...

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Detalles Bibliográficos
Autores principales:	Nguyen, Linh, Dang, Cuong C, Ballester, Pedro J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000Research 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310525/ https://www.ncbi.nlm.nih.gov/pubmed/28299173 http://dx.doi.org/10.12688/f1000research.10529.2

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