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Evolutionary adaptation of the sensitivity of connexin26 hemichannels to CO(2)

CO(2) readily combines with H(2)O to form [Image: see text] and H(+). Because an increase of only 100 nM in the concentration of H(+) (a decrease of 0.1 unit of pH) in blood can prove fatal, the regulated excretion of CO(2) during breathing is an essential life-preserving process. In rodents and hum...

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Detalles Bibliográficos
Autores principales: de Wolf, Elizabeth, Cook, Jonathan, Dale, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310615/
https://www.ncbi.nlm.nih.gov/pubmed/28148750
http://dx.doi.org/10.1098/rspb.2016.2723

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