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Spotlight on crizotinib in the first-line treatment of ALK-positive advanced non-small-cell lung cancer: patients selection and perspectives

Around 4% of advanced non-small-cell lung cancers (NSCLCs) have an ALK rearrangement at the time of diagnosis. This molecular feature is more frequent in young patients, with no/light smoking habit and with adenocarcinoma pathological subtype. Crizotinib is a tyrosine kinase inhibitor, targeting ALK...

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Detalles Bibliográficos
Autores principales:	Leprieur, Etienne Giroux, Fallet, Vincent, Cadranel, Jacques, Wislez, Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310701/ https://www.ncbi.nlm.nih.gov/pubmed/28210164 http://dx.doi.org/10.2147/LCTT.S99303

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