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A simplified mathematical model of directional DNA site-specific recombination by serine integrases

Serine integrases catalyse site-specific recombination to integrate and excise bacteriophage genomes into and out of their host's genome. These enzymes exhibit remarkable directionality; in the presence of the integrase alone, recombination between attP and attB DNA sites is efficient and irrev...

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Detalles Bibliográficos
Autores principales: Pokhilko, Alexandra, Zhao, Jia, Stark, W. Marshall, Colloms, Sean D., Ebenhöh, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310728/
https://www.ncbi.nlm.nih.gov/pubmed/28077763
http://dx.doi.org/10.1098/rsif.2016.0618

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