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A simplified mathematical model of directional DNA site-specific recombination by serine integrases

Serine integrases catalyse site-specific recombination to integrate and excise bacteriophage genomes into and out of their host's genome. These enzymes exhibit remarkable directionality; in the presence of the integrase alone, recombination between attP and attB DNA sites is efficient and irrev...

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Detalles Bibliográficos
Autores principales:	Pokhilko, Alexandra, Zhao, Jia, Stark, W. Marshall, Colloms, Sean D., Ebenhöh, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2017
Materias:	Life Sciences–Mathematics interface
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310728/ https://www.ncbi.nlm.nih.gov/pubmed/28077763 http://dx.doi.org/10.1098/rsif.2016.0618

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