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Secondary-structure prediction revisited: Theoretical β-sheet propensity and coil propensity represent structures of amyloids and aid in elucidating phenomena involved in interspecies transmission of prions
Prions are unique infectious agents, consisting solely of abnormally-folded prion protein (PrP(Sc)). However, they possess virus-like features, including strain diversity, the ability to adapt to new hosts and to be altered evolutionarily. Because prions lack genetic material (DNA and RNA), these bi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310760/ https://www.ncbi.nlm.nih.gov/pubmed/28199368 http://dx.doi.org/10.1371/journal.pone.0171974 |