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A novel mycobacterial In Vitro infection assay identifies differences of induced macrophage apoptosis between CD4(+) and CD8(+) T cells

Macrophages are natural host cells for pathogenic mycobacteria, like Mycobacterium tuberculosis (M.tb). Immune surveillance by T cells and interaction with M.tb infected macrophages is crucial for protection against M.tb reactivation and development of active tuberculosis. Several factors play a rol...

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Detalles Bibliográficos
Autores principales: Nkwouano, Vanesa, Witkowski, Sven, Rehberg, Nidja, Kalscheuer, Rainer, Nausch, Norman, Mayatepek, Ertan, Jacobsen, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310865/
https://www.ncbi.nlm.nih.gov/pubmed/28199374
http://dx.doi.org/10.1371/journal.pone.0171817

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