Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

Coronaviruses are of veterinary and medical importance and include highly pathogenic zoonotic viruses, such as SARS-CoV and MERS-CoV. They are known to efficiently evade early innate immune responses, manifesting in almost negligible expression of type-I interferons (IFN-I). This evasion strategy su...

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Detalles Bibliográficos
Autores principales: Kindler, Eveline, Gil-Cruz, Cristina, Spanier, Julia, Li, Yize, Wilhelm, Jochen, Rabouw, Huib H., Züst, Roland, Hwang, Mihyun, V’kovski, Philip, Stalder, Hanspeter, Marti, Sabrina, Habjan, Matthias, Cervantes-Barragan, Luisa, Elliot, Ruth, Karl, Nadja, Gaughan, Christina, van Kuppeveld, Frank J. M., Silverman, Robert H., Keller, Markus, Ludewig, Burkhard, Bergmann, Cornelia C., Ziebuhr, John, Weiss, Susan R., Kalinke, Ulrich, Thiel, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310923/
https://www.ncbi.nlm.nih.gov/pubmed/28158275
http://dx.doi.org/10.1371/journal.ppat.1006195

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