A novel FOXM1 isoform, FOXM1D, promotes epithelial–mesenchymal transition and metastasis through ROCKs activation in colorectal cancer

Epithelial–mesenchymal transition (EMT) is a critical event in metastasis of colorectal cancer (CRC). Rho/ROCKs signaling has a pivotal role in orchestrating actin cytoskeleton, leading to EMT and cancer invasion. However, the underlying mechanisms for ROCKs activation are not fully understood. Here...

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Detalles Bibliográficos
Autores principales: Zhang, X, Zhang, L, Du, Y, Zheng, H, Zhang, P, Sun, Y, Wang, Y, Chen, J, Ding, P, Wang, N, Yang, C, Huang, T, Yao, X, Qiao, Q, Gu, H, Cai, G, Cai, S, Zhou, X, Hu, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311249/
https://www.ncbi.nlm.nih.gov/pubmed/27399334
http://dx.doi.org/10.1038/onc.2016.249

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