microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network

microRNA (miRNA) dysregulation is a common feature of cancer cells, but the complex roles of miRNAs in cancer are not fully elucidated. Here, we used functional genomics to identify oncogenic miRNAs in non-small cell lung cancer and evaluate their impact on response to epidermal growth factor (EGFR)...

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Detalles Bibliográficos
Autores principales: Zhou, Y, Frings, O, Branca, R M, Boekel, J, le Sage, C, Fredlund, E, Agami, R, Orre, L M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311252/
https://www.ncbi.nlm.nih.gov/pubmed/27477696
http://dx.doi.org/10.1038/onc.2016.242

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