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Mesenchymal to Epithelial Transition Mediated by CDH1 Promotes Spontaneous Reprogramming of Male Germline Stem Cells to Pluripotency

Cultured spermatogonial stem cells (GSCs) can spontaneously form pluripotent cells in certain culture conditions. However, GSC reprogramming is a rare event that is largely unexplained. We show GSCs have high expression of mesenchymal to epithelial transition (MET) suppressors resulting in a develop...

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Detalles Bibliográficos
Autores principales: An, Junhui, Zheng, Yu, Dann, Christina Tenenhaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311464/
https://www.ncbi.nlm.nih.gov/pubmed/28065642
http://dx.doi.org/10.1016/j.stemcr.2016.12.006