Impaired inactivation of digestive proteases: The possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury

Recent study shows that germ-free and antibiotic-treated animals are highly susceptible to gut epithelial injury. This paper addresses that impaired inactivation of digestive proteases may be the key factor for the increased susceptibility.

Detalles Bibliográficos
Autor principal: Qin, Xiaofa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Field Of Vision
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311466/
https://www.ncbi.nlm.nih.gov/pubmed/28251033
http://dx.doi.org/10.4291/wjgp.v8.i1.1
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author Qin, Xiaofa
author_facet Qin, Xiaofa
author_sort Qin, Xiaofa
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description Recent study shows that germ-free and antibiotic-treated animals are highly susceptible to gut epithelial injury. This paper addresses that impaired inactivation of digestive proteases may be the key factor for the increased susceptibility.
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spelling pubmed-53114662017-03-01 Impaired inactivation of digestive proteases: The possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury Qin, Xiaofa World J Gastrointest Pathophysiol Field Of Vision Recent study shows that germ-free and antibiotic-treated animals are highly susceptible to gut epithelial injury. This paper addresses that impaired inactivation of digestive proteases may be the key factor for the increased susceptibility. Baishideng Publishing Group Inc 2017-02-15 2017-02-15 /pmc/articles/PMC5311466/ /pubmed/28251033 http://dx.doi.org/10.4291/wjgp.v8.i1.1 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Field Of Vision
Qin, Xiaofa
Impaired inactivation of digestive proteases: The possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury
title Impaired inactivation of digestive proteases: The possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury
title_full Impaired inactivation of digestive proteases: The possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury
title_fullStr Impaired inactivation of digestive proteases: The possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury
title_full_unstemmed Impaired inactivation of digestive proteases: The possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury
title_short Impaired inactivation of digestive proteases: The possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury
title_sort impaired inactivation of digestive proteases: the possible key factor for the high susceptibility of germ-free and antibiotic-treated animals to gut epithelial injury
topic Field Of Vision
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311466/
https://www.ncbi.nlm.nih.gov/pubmed/28251033
http://dx.doi.org/10.4291/wjgp.v8.i1.1
work_keys_str_mv AT qinxiaofa impairedinactivationofdigestiveproteasesthepossiblekeyfactorforthehighsusceptibilityofgermfreeandantibiotictreatedanimalstogutepithelialinjury

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