PDGFRα(+) Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors

In early mouse pre-implantation development, primitive endoderm (PrE) precursors are platelet-derived growth factor receptor alpha (PDGFRα) positive. Here, we demonstrated that cultured mouse embryonic stem cells (mESCs) express PDGFRα heterogeneously, fluctuating between a PDGFRα+ (PrE-primed) and...

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Detalles Bibliográficos
Autores principales: Lo Nigro, Antonio, de Jaime-Soguero, Anchel, Khoueiry, Rita, Cho, Dong Seong, Ferlazzo, Giorgia Maria, Perini, Ilaria, Abon Escalona, Vanesa, Aranguren, Xabier Lopez, Chuva de Sousa Lopes, Susana M., Koh, Kian Peng, Conaldi, Pier Giulio, Hu, Wei-Shou, Zwijsen, An, Lluis, Frederic, Verfaillie, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311469/
https://www.ncbi.nlm.nih.gov/pubmed/28089671
http://dx.doi.org/10.1016/j.stemcr.2016.12.010

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