The eIF3 complex of Trypanosoma brucei: composition conservation does not imply the conservation of structural assembly and subunits function

The multisubunit eukaryotic initiation factor 3 (eIF3) plays multiple roles in translation but is poorly understood in trypanosomes. The putative subunits eIF3a and eIF3f of Trypanosoma brucei (TbIF3a and TbIF3f) were overexpressed and purified, and 11 subunits were identified, TbIF3a through l minu...

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Detalles Bibliográficos
Autores principales: Li, Kunrao, Zhou, Shuru, Guo, Qixuan, Chen, Xin, Lai, De-hua, Lun, Zhao-rong, Guo, Xuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311491/
https://www.ncbi.nlm.nih.gov/pubmed/27932584
http://dx.doi.org/10.1261/rna.058651.116

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