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S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates

The 3-methylcytidine (m(3)C) modification is ubiquitous in eukaryotic tRNA, widely found at C(32) in the anticodon loop of tRNA(Thr), tRNA(Ser), and some tRNA(Arg) species, as well as in the variable loop (V-loop) of certain tRNA(Ser) species. In the yeast Saccharomyces cerevisiae, formation of m(3)...

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Detalles Bibliográficos
Autores principales: Han, Lu, Marcus, Erin, D'Silva, Sonia, Phizicky, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311504/
https://www.ncbi.nlm.nih.gov/pubmed/28003514
http://dx.doi.org/10.1261/rna.059667.116

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