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Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice

Transient receptor potential vanilloid 4 (TRPV4) is a Ca(2+)-permeable nonselective cation channel and can be activated during ischemia/reperfusion (I/R). This study tested whether blockade of TRPV4 can alleviate myocardial I/R injury in mice. TRPV4 expression began to increase at 1 h, reached stati...

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Detalles Bibliográficos
Autores principales:	Dong, Qian, Li, Jing, Wu, Qiong-feng, Zhao, Ning, Qian, Cheng, Ding, Dan, Wang, Bin-bin, Chen, Lei, Guo, Ke-Fang, Fu, Dehao, Han, Bing, Liao, Yu-Hua, Du, Yi-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311718/ https://www.ncbi.nlm.nih.gov/pubmed/28205608 http://dx.doi.org/10.1038/srep42678

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