Cargando…

Safety and efficacy of lobaplatin combined with 5-fluorouracil as first-line induction chemotherapy followed by lobaplatin-radiotherapy in locally advanced nasopharyngeal carcinoma: preliminary results of a prospective phase II trial

BACKGROUND: Due to improvements in imaging and radiological techniques as well as the use of chemotherapy, distant metastasis has become the predominant mode of treatment failure in patients with locally advanced nasopharyngeal carcinoma (LA-NPC). Platinum-based systemic chemotherapy has shown survi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ke, Liang-Ru, Xia, Wei-Xiong, Qiu, Wen-Ze, Huang, Xin-Jun, Yang, Jing, Yu, Ya-Hui, Liang, Hu, Liu, Guo-Ying, Ye, Yan-Fang, Xiang, Yan-Qun, Guo, Xiang, Lv, Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311839/ https://www.ncbi.nlm.nih.gov/pubmed/28202000 http://dx.doi.org/10.1186/s12885-017-3080-4

Ejemplares similares

Induction chemotherapy with albumin-bound paclitaxel plus lobaplatin followed by concurrent radiochemotherapy for locally advanced esophageal cancer
por: Yan, Mao-Hui, et al.
Publicado: (2021)

Lobaplatin: Multiple toxicities: case report.
Publicado: (2020)

Retrospective study of the efficacy and toxicity of lobaplatin in combined chemotherapy for metastatic breast cancer
por: Wu, Yuan, et al.
Publicado: (2019)

Multicentre Comparison of the Toxicity and Effectiveness of Lobaplatin-Based Versus Cisplatin-Based Adjuvant Chemotherapy in Oesophageal Carcinoma
por: Zheng, Yan, et al.
Publicado: (2021)

The Efficacy and Toxicity of Lobaplatin-contained Chemotherapy in Extensive-stage Small-cell Lung Cancer
por: Zhou, Ning-ning, et al.
Publicado: (2018)

Efficacy and toxicity of three concurrent chemoradiotherapy regimens in treating nasopharyngeal carcinoma: Comparison among cisplatin, nedaplatin, and lobaplatin
por: Liang, Xuexia, et al.
Publicado: (2022)

Efficacy and Safety of Lobaplatin-TACE in the Treatment of Primary Hepatocellular Carcinoma: A Retrospective Study
por: Lu, Haohao, et al.
Publicado: (2023)

Retrospective study of the efficacy and toxicity of lobaplatin‐etoposide chemotherapy in small cell lung cancer
por: Gu, Liyan, et al.
Publicado: (2019)

Lobaplatin in Prophylactic Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer: Safety and Efficacy Profiles
por: Zhong, Yuxin, et al.
Publicado: (2020)

Effect of induction chemotherapy with cisplatin, fluorouracil, with or without taxane on locoregionally advanced nasopharyngeal carcinoma: a retrospective, propensity score-matched analysis
por: Liu, Guo-Ying, et al.
Publicado: (2018)

Comparison of the therapeutic effects of lobaplatin and carboplatin on retinoblastoma in vitro and in vivo
por: Zhou, Zijun, et al.
Publicado: (2020)

Phase II and pharmacokinetic study of lobaplatin in patients with relapsed ovarian cancer.
por: Gietema, J. A., et al.
Publicado: (1995)

Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells
por: Wu, Qiong, et al.
Publicado: (2010)

Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
por: Yu, Junhui, et al.
Publicado: (2019)

Lobaplatin for the treatment of SK-MES-1 lung squamous cell line in vitro and in vivo
por: Zhang, Hongming, et al.
Publicado: (2016)

Lobaplatin Inhibits the Proliferation of Hepatollular Carcinoma Through P53 Apoptosis Axis
por: Wang, Ying, et al.
Publicado: (2012)

Pilot study of docetaxel combined with lobaplatin or gemcitabine for recurrent and metastatic breast cancer
por: Li, Fenghu, et al.
Publicado: (2019)

Population pharmacokinetics and individualized lobaplatin regimen for the treatment of Chinese small cell lung cancer in the elderly
por: Cheng, Ying, et al.
Publicado: (2019)

Lobaplatin-Based Hyperthermic Intraperitoneal Chemotherapy for Patients with Peritoneal Metastasis from Appendiceal and Colorectal Cancer: Safety and Efficacy Profiles
por: Pei, Wei, et al.
Publicado: (2020)

Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy with lobaplatin and docetaxel improves survival for patients with peritoneal carcinomatosis from abdominal and pelvic malignancies
por: Wu, Hai-Tao, et al.
Publicado: (2016)

The anti-tumor effects of the combination of microwave hyperthermia and lobaplatin against breast cancer cells in vitro and in vivo
por: Li, Xiaohu, et al.
Publicado: (2022)

Acute pancreatitis induced by etoposide–lobaplatin combination chemotherapy used for the treatment of lung cancer: A case report and literature review
por: Cao, Cheng-Liang, et al.
Publicado: (2017)

Lobaplatin-based prophylactic hyperthermic intraperitoneal chemotherapy for T4 gastric cancer patients: A retrospective clinical study
por: Zhong, Yuxin, et al.
Publicado: (2023)

Efficacy of transcatheter arterial chemoembolization using pirarubicin-loaded microspheres combined with lobaplatin for primary liver cancer
por: Zhang, Chao, et al.
Publicado: (2022)

Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX
por: Cao, Hongwen, et al.
Publicado: (2019)

Lobaplatin inhibits breast cancer progression, cell proliferation while it induces cell apoptosis by downregulating MTDH expression
por: Tian, Wuguo, et al.
Publicado: (2018)

A randomized and open-label phase II trial reports the efficacy of neoadjuvant lobaplatin in breast cancer
por: Wu, Xiujuan, et al.
Publicado: (2018)

Protein and Signaling Pathway Responses to rhIL-6 Intervention Before Lobaplatin Treatment in Osteosarcoma Cells
por: Wang, Huan, et al.
Publicado: (2021)

Lobaplatin-based regimens outperform cisplatin for metastatic breast cancer after anthracyclines and taxanes treatment
por: Wang, Zhipeng, et al.
Publicado: (2018)

Stage-specific concurrent chemoradiotherapy with or without induction chemotherapy for locoregionally advanced nasopharyngeal carcinoma: a retrospective, population-based study
por: Xia, Wei-Xiong, et al.
Publicado: (2019)

Intrapleural combination therapy with lobaplatin and erythromycin for non‐small cell lung cancer‐mediated malignant pleural effusion
por: Xu, Lisheng, et al.
Publicado: (2018)

A prospective, open-label, multicenter phase IV clinical trial on the safety and efficacy of lobaplatin-based chemotherapy in advanced breast cancer
por: Yan, Min, et al.
Publicado: (2022)

Paclitaxel increases the sensitivity of lung cancer cells to lobaplatin via PI3K/Akt pathway
por: Ma, Dongjie, et al.
Publicado: (2018)

Hematological Toxicities of Concurrent Chemoradiotherapies in Head and Neck Cancers: Comparison Among Cisplatin, Nedaplatin, Lobaplatin, and Nimotuzumab
por: Wu, Qiuji, et al.
Publicado: (2021)

A study of the efficacy and tolerability of capecitabine and lobaplatin in advanced HER-2 negative breast cancer patients
por: Yuan, Yuan, et al.
Publicado: (2021)

Paclitaxel increases the sensitivity of lung cancer cells to lobaplatin via PI3K/Akt pathway
por: Ma, Dongjie, et al.
Publicado: (2021)

A retrospective study of 606 cases of nasopharyngeal carcinoma with or without oropharyngeal candidiasis during radiotherapy
por: Qiu, Wen-Ze, et al.
Publicado: (2017)

Comparison of the short-term efficacy between docetaxel plus carboplatin and 5-fluorouracil plus carboplatin in locoregionally advanced nasopharyngeal carcinoma
por: Lv, Xing, et al.
Publicado: (2016)

Thoracic perfusion of lobaplatin combined with endostar for treating malignant pleural effusions: A meta-analysis and systematic review
por: Wang, Cheng-Qian, et al.
Publicado: (2022)

Lobaplatin-based neoadjuvant chemotherapy for triple-negative breast cancer: a 5-year follow-up of a randomized, open-label, phase II trial
por: Yan, Wenting, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vttedtoois2510pds36ch94pde