Tim-3 inhibits macrophage control of Listeria monocytogenes by inhibiting Nrf2

T cell immunoglobulin mucin-3 (Tim-3) is an immune checkpoint inhibitor and its dysregulation has been related to T cell tolerance and many immune disorders, such as tumors and infection tolerance. However, the physiopathology roles of Tim-3 in innate immunity remain elusive. Here, we demonstrate th...

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Detalles Bibliográficos
Autores principales: Wang, Zhiding, Sun, Dejun, Chen, Guojiang, Li, Ge, Dou, Shuaijie, Wang, Renxi, Xiao, He, Hou, Chunmei, Li, Yan, Feng, Jiannan, Shen, Beifen, Han, Gencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311873/
https://www.ncbi.nlm.nih.gov/pubmed/28205579
http://dx.doi.org/10.1038/srep42095

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