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Polymorphisms of toll-like receptors 2 and 9 and severity and prognosis of bacterial meningitis in Chinese children

Toll-like receptors (TLRs) play a crucial role in innate immunity, protecting the host from bacterial pathogens. We investigated whether bacterial meningitis (BM) in children was associated with gene polymorphisms in TLR2 (rs3804099), TLR3 (rs3775291 and rs3775290) and TLR9 (rs352139 and rs352140)....

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Detalles Bibliográficos
Autores principales: Zhang, Pingping, Zhang, Nan, Liu, Linlin, Zheng, Kai, Zhu, Liang, Zhu, Junping, Cao, Lina, Jiang, Yiyuan, Liu, Gang, He, Qiushui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311876/
https://www.ncbi.nlm.nih.gov/pubmed/28202935
http://dx.doi.org/10.1038/srep42796