Neuronally-directed effects of RXR activation in a mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by extensive neuron loss that accompanies profound impairments in memory and cognition. We examined the neuronally directed effects of the retinoid X receptor agonist bexarotene in an aggressive model of AD. We report that a two week treatment of 3.5 month o...

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Detalles Bibliográficos
Autores principales: Mariani, M. M., Malm, T., Lamb, R., Jay, T. R., Neilson, L., Casali, B., Medarametla, L., Landreth, G. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311933/
https://www.ncbi.nlm.nih.gov/pubmed/28205585
http://dx.doi.org/10.1038/srep42270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311933/
https://www.ncbi.nlm.nih.gov/pubmed/28205585
http://dx.doi.org/10.1038/srep42270

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