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Identification of a substrate domain that determines system specificity in mycobacterial type VII secretion systems

Type VII secretion (T7S) systems are specialized machineries used by mycobacterial pathogens to transport important virulence factors across their highly hydrophobic cell envelope. There are up to five mycobacterial T7S systems, named ESX-1 to ESX-5, at least three of which specifically secrete a di...

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Detalles Bibliográficos
Autores principales:	Phan, Trang H., Ummels, Roy, Bitter, Wilbert, Houben, Edith N. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311947/ https://www.ncbi.nlm.nih.gov/pubmed/28205541 http://dx.doi.org/10.1038/srep42704

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