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The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms

Autophagy functions as a main route for the degradation of superfluous and damaged constituents of the cytoplasm. Defects in autophagy are implicated in the development of various age-dependent degenerative disorders such as cancer, neurodegeneration and tissue atrophy, and in accelerated aging. To...

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Detalles Bibliográficos
Autores principales: Kovács, Tibor, Billes, Viktor, Komlós, Marcell, Hotzi, Bernadette, Manzéger, Anna, Tarnóci, Anna, Papp, Diána, Szikszai, Fanni, Szinyákovics, Janka, Rácz, Ákos, Noszál, Béla, Veszelka, Szilvia, Walter, Fruzsina R., Deli, Mária A., Hackler, Laszlo, Alfoldi, Robert, Huzian, Orsolya, Puskas, Laszlo G., Liliom, Hanna, Tárnok, Krisztián, Schlett, Katalin, Borsy, Adrienn, Welker, Ervin, Kovács, Attila L., Pádár, Zsolt, Erdős, Attila, Legradi, Adam, Bjelik, Annamaria, Gulya, Károly, Gulyás, Balázs, Vellai, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311965/
https://www.ncbi.nlm.nih.gov/pubmed/28205624
http://dx.doi.org/10.1038/srep42014