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The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms
Autophagy functions as a main route for the degradation of superfluous and damaged constituents of the cytoplasm. Defects in autophagy are implicated in the development of various age-dependent degenerative disorders such as cancer, neurodegeneration and tissue atrophy, and in accelerated aging. To...
Autores principales: | Kovács, Tibor, Billes, Viktor, Komlós, Marcell, Hotzi, Bernadette, Manzéger, Anna, Tarnóci, Anna, Papp, Diána, Szikszai, Fanni, Szinyákovics, Janka, Rácz, Ákos, Noszál, Béla, Veszelka, Szilvia, Walter, Fruzsina R., Deli, Mária A., Hackler, Laszlo, Alfoldi, Robert, Huzian, Orsolya, Puskas, Laszlo G., Liliom, Hanna, Tárnok, Krisztián, Schlett, Katalin, Borsy, Adrienn, Welker, Ervin, Kovács, Attila L., Pádár, Zsolt, Erdős, Attila, Legradi, Adam, Bjelik, Annamaria, Gulya, Károly, Gulyás, Balázs, Vellai, Tibor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311965/ https://www.ncbi.nlm.nih.gov/pubmed/28205624 http://dx.doi.org/10.1038/srep42014 |
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