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Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation
Hypersecretion of mucus is an important component of airway remodeling and contributes to the mucus plugs and airflow obstruction associated with severe asthma phenotypes. Lyn has been shown to down-regulate allergen-induced airway inflammation. However, the role of Lyn in mucin gene expression rema...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312001/ https://www.ncbi.nlm.nih.gov/pubmed/28205598 http://dx.doi.org/10.1038/srep42675 |