Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation

Hypersecretion of mucus is an important component of airway remodeling and contributes to the mucus plugs and airflow obstruction associated with severe asthma phenotypes. Lyn has been shown to down-regulate allergen-induced airway inflammation. However, the role of Lyn in mucin gene expression rema...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyun, Li, Yin, Luo, Deyu, Wang, Xing, Zhang, Yun, Liu, Zhigang, Zhong, Nanshan, Wu, Min, Li, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312001/
https://www.ncbi.nlm.nih.gov/pubmed/28205598
http://dx.doi.org/10.1038/srep42675

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