Cargando…

FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication

The life cycle of human papillomavirus (HPV) is dependent on the differentiation state of its host cell. HPV genomes are maintained as low-copy episomes in basal epithelial cells and amplified to thousands of copies per cell in differentiated layers. Replication of high-risk HPVs requires the activa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spriggs, Chelsey C., Laimins, Laimonis A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312087/ https://www.ncbi.nlm.nih.gov/pubmed/28196964 http://dx.doi.org/10.1128/mBio.02340-16

Ejemplares similares

Human Papillomavirus and the DNA Damage Response: Exploiting Host Repair Pathways for Viral Replication
por: Spriggs, Chelsey C., et al.
Publicado: (2017)

Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification
por: Mehta, Kavi, et al.
Publicado: (2018)

Genomic Instability and DNA Damage Repair Pathways Induced by Human Papillomaviruses
por: Kono, Takeyuki, et al.
Publicado: (2021)

Regulation of the Human Papillomavirus Life Cycle by DNA Damage Repair Pathways and Epigenetic Factors
por: Albert, Ekaterina, et al.
Publicado: (2020)

The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replication by Modulating Histone Acetylation and Recruitment of DNA Damage Factors NBS1 and Rad51 to Viral Genomes
por: Langsfeld, Erika S., et al.
Publicado: (2015)

Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation
por: Moody, Cary A., et al.
Publicado: (2009)

Human Papillomaviruses Target the DNA Damage Repair and Innate Immune Response Pathways to Allow for Persistent Infection
por: Gusho, Elona, et al.
Publicado: (2021)

Topoisomerase 2β Induces DNA Breaks To Regulate Human Papillomavirus Replication
por: Kaminski, Paul, et al.
Publicado: (2021)

STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication
por: Hong, Shiyuan, et al.
Publicado: (2015)

Human papillomaviruses sensitize cells to DNA damage induced apoptosis by targeting the innate immune sensor cGAS
por: Gusho, Elona, et al.
Publicado: (2022)

Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle
por: Gunasekharan, Vignesh Kumar, et al.
Publicado: (2016)

Interferon-Inducible Genes Are Major Targets of Human Papillomavirus Type 31: Insights from Microarray Analysis
por: Chang, Yijan E., et al.
Publicado: (2001)

The JAK-STAT Transcriptional Regulator, STAT-5, Activates the ATM DNA Damage Pathway to Induce HPV 31 Genome Amplification upon Epithelial Differentiation
por: Hong, Shiyuan, et al.
Publicado: (2013)

FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair
por: Alcón, Pablo, et al.
Publicado: (2020)

Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair
por: Oestergaard, Vibe H., et al.
Publicado: (2007)

Human Papillomaviruses Activate and Recruit SMC1 Cohesin Proteins for the Differentiation-Dependent Life Cycle through Association with CTCF Insulators
por: Mehta, Kavi, et al.
Publicado: (2015)

Pathogenesis of Human Papillomaviruses Requires the ATR/p62 Autophagy-Related Pathway
por: Hong, Shiyuan, et al.
Publicado: (2020)

FANCD2 limits acetaldehyde‐induced genomic instability during DNA replication in esophageal keratinocytes
por: Peake, Jasmine D., et al.
Publicado: (2021)

FANCD2 and DNA Damage
por: Nepal, Manoj, et al.
Publicado: (2017)

High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2
por: Khanal, Sujita, et al.
Publicado: (2019)

Mechanisms regulating expression of the HPV 31 L1 and L2 capsid proteins and pseudovirion entry
por: Hindmarsh, Patrick L, et al.
Publicado: (2007)

Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination
por: Liang, Zhuobin, et al.
Publicado: (2019)

The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2
por: Liang, Chih-Chao, et al.
Publicado: (2016)

FANCD2 influences replication fork processes and genome stability in response to clustered DSBs
por: Zhu, Jiayun, et al.
Publicado: (2015)

FANCD2 limits replication stress and genome instability in cells lacking BRCA2
por: Michl, Johanna, et al.
Publicado: (2016)

Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA
por: Longerich, Simonne, et al.
Publicado: (2014)

FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures
por: Yuan, Fenghua, et al.
Publicado: (2009)

The identification of FANCD2 DNA binding domains reveals nuclear localization sequences
por: Niraj, Joshi, et al.
Publicado: (2017)

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress
por: Yang, Yeran, et al.
Publicado: (2015)

FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability
por: Liu, Wenpeng, et al.
Publicado: (2023)

p53-dependent R-loop formation and HPV pathogenesis
por: Templeton, Conor Winslow, et al.
Publicado: (2023)

Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage
por: Lopez-Martinez, David, et al.
Publicado: (2019)

Viral trans-factor independent replication of human papillomavirus genomes
por: Pittayakhajonwut, Daraporn, et al.
Publicado: (2010)

Topoisomerase IIβ-binding protein 1 activates expression of E2F1 and p73 in HPV positive cells for genome amplification upon epithelial differentiation
por: Hong, Shiyuan, et al.
Publicado: (2019)

FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery
por: Chaudhury, Indrajit, et al.
Publicado: (2013)

FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ
por: Kondo, Natsuko, et al.
Publicado: (2011)

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI
por: Sato, Koichi, et al.
Publicado: (2012)

Replication stress induces accumulation of FANCD2 at central region of large fragile genes
por: Okamoto, Yusuke, et al.
Publicado: (2018)

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end
por: Sato, Koichi, et al.
Publicado: (2016)

Correction: FANCD1/BRCA2 Plays Predominant Role in the Repair of DNA Damage Induced by ACNU or TMZ
por: Kondo, Natsuko, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_e84nr70l1c8c7ke9r0h14ud44g