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Preclinical Efficacy Failure of Human CNS-Derived Stem Cells for Use in the Pathway Study of Cervical Spinal Cord Injury

We previously showed the efficacy of multiple research cell lines (RCLs) of human CNS neural stem cells (HuCNS-SCs) in mouse and rat models of thoracic spinal cord injury (SCI), supporting a thoracic SCI clinical trial. Experts recommend in vivo preclinical testing of the intended clinical cell lot/...

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Detalles Bibliográficos
Autores principales: Anderson, Aileen J., Piltti, Katja M., Hooshmand, Mitra J., Nishi, Rebecca A., Cummings, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312249/
https://www.ncbi.nlm.nih.gov/pubmed/28199829
http://dx.doi.org/10.1016/j.stemcr.2016.12.018