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SCA-1 Labels a Subset of Estrogen-Responsive Bipotential Repopulating Cells within the CD24(+) CD49f(hi) Mammary Stem Cell-Enriched Compartment
Estrogen stimulates breast development during puberty and mammary tumors in adulthood through estrogen receptor-α (ERα). These effects are proposed to occur via ERα(+) luminal cells and not the mammary stem cells (MaSCs) that are ERα(neg). Since ERα(+) luminal cells express stem cell antigen-1 (SCA-...
Autores principales: | Dall, Genevieve V., Vieusseux, Jessica L., Korach, Kenneth S., Arao, Yukitomo, Hewitt, Sylvia C., Hamilton, Katherine J., Dzierzak, Elaine, Boon, Wah Chin, Simpson, Evan R., Ramsay, Robert G., Stein, Torsten, Morris, Joanne S., Anderson, Robin L., Risbridger, Gail P., Britt, Kara L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312257/ https://www.ncbi.nlm.nih.gov/pubmed/28132885 http://dx.doi.org/10.1016/j.stemcr.2016.12.022 |
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