Loss of prolyl hydroxylase domain protein 2 in vascular endothelium increases pericyte coverage and promotes pulmonary arterial remodeling

Pulmonary arterial hypertension (PAH) is a leading cause of heart failure. Although pulmonary endothelial dysfunction plays a crucial role in the progression of the PAH, the underlying mechanisms are poorly understood. The HIF-α hydroxylase system is a key player in the regulation of vascular remode...

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Detalles Bibliográficos
Autores principales: Wang, Shuo, Zeng, Heng, Xie, Xue-Jiao, Tao, Yong-Kang, He, Xiaochen, Roman, Richard J., Aschner, Judy L., Chen, Jian-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312280/
https://www.ncbi.nlm.nih.gov/pubmed/27613846
http://dx.doi.org/10.18632/oncotarget.11585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312280/
https://www.ncbi.nlm.nih.gov/pubmed/27613846
http://dx.doi.org/10.18632/oncotarget.11585

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