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hERG1/Kv11.1 activation stimulates transcription of p21(waf/cip) in breast cancer cells via a calcineurin-dependent mechanism
The function of Kv11.1 is emerging in breast cancer biology, as a growing body of evidence indicates that the hERG1/Kv11.1 potassium channel is aberrantly expressed in several cancer types including breast cancers. The biological effects of Kv11.1 channel blockers and their associated side effects a...
Autores principales: | Perez-Neut, Mathew, Rao, Vidhya R., Gentile, Saverio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312283/ https://www.ncbi.nlm.nih.gov/pubmed/25945833 http://dx.doi.org/10.18632/oncotarget.3797 |
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