Co-expression modules of NF1, PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinases

Inter-individual variability causing elevated signaling of receptor tyrosine kinases (RTK) may have hampered the efficacy of targeted therapies. We developed a molecular signature for clustering adult diffuse gliomas based on the extent of RTK pathway activities. Glioma gene modules co-expressed wit...

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Detalles Bibliográficos
Autores principales: Zhang, Wanyu, Lv, Yuhong, Xue, Yang, Wu, Chenxing, Yao, Kun, Zhang, Chuanbao, Jin, Qiang, Huang, Rong, Li, Jiuyi, Sun, Yingyu, Su, Xiaodong, Jiang, Tao, Fan, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312298/
https://www.ncbi.nlm.nih.gov/pubmed/27385209
http://dx.doi.org/10.18632/oncotarget.10359

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