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Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells
Exosomes are small (30-100nm) vesicles secreted from all cell types serving as inter-cell communicators and affecting biological processes in “recipient” cells upon their uptake. The current study demonstrates for the first time that hTERT mRNA, the transcript of the enzyme telomerase, is shuttled f...
Autores principales: | Gutkin, Anna, Uziel, Orit, Beery, Einat, Nordenberg, Jardena, Pinchasi, Maria, Goldvaser, Hadar, Henick, Steven, Goldberg, Michal, Lahav, Meir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312303/ https://www.ncbi.nlm.nih.gov/pubmed/27385095 http://dx.doi.org/10.18632/oncotarget.10384 |
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