Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia

Deregulation of microRNAs' expression frequently occurs in acute myeloid leukemia (AML). Lower miR-181a expression is associated with worse outcomes, but the exact mechanisms by which miR-181a mediates this effect remain elusive. Aberrant activation of the RAS pathway contributes to myeloid leu...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Xiaomeng, Schwind, Sebastian, Santhanam, Ramasamy, Eisfeld, Ann-Kathrin, Chiang, Chi-ling, Lankenau, Malori, Yu, Bo, Hoellerbauer, Pia, Jin, Yan, Tarighat, Somayeh S., Khalife, Jihane, Walker, Alison, Perrotti, Danilo, Bloomfield, Clara D., Wang, Hongyan, Lee, Robert J., Lee, Ly James, Marcucci, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312311/
https://www.ncbi.nlm.nih.gov/pubmed/27517749
http://dx.doi.org/10.18632/oncotarget.11150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312311/
https://www.ncbi.nlm.nih.gov/pubmed/27517749
http://dx.doi.org/10.18632/oncotarget.11150

Ejemplares similares