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Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia

Deregulation of microRNAs' expression frequently occurs in acute myeloid leukemia (AML). Lower miR-181a expression is associated with worse outcomes, but the exact mechanisms by which miR-181a mediates this effect remain elusive. Aberrant activation of the RAS pathway contributes to myeloid leu...

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Detalles Bibliográficos
Autores principales:	Huang, Xiaomeng, Schwind, Sebastian, Santhanam, Ramasamy, Eisfeld, Ann-Kathrin, Chiang, Chi-ling, Lankenau, Malori, Yu, Bo, Hoellerbauer, Pia, Jin, Yan, Tarighat, Somayeh S., Khalife, Jihane, Walker, Alison, Perrotti, Danilo, Bloomfield, Clara D., Wang, Hongyan, Lee, Robert J., Lee, Ly James, Marcucci, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312311/ https://www.ncbi.nlm.nih.gov/pubmed/27517749 http://dx.doi.org/10.18632/oncotarget.11150

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