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IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens

MELOE-1 and MELOE-2, two highly specific melanoma antigens involved in T cell immunosurveillance are produced by IRES-dependent translation of the long « non coding » and polycistronic RNA, meloe. In the present study, we document the expression of an additional ORF, MELOE-3, located in the 5′ regio...

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Detalles Bibliográficos
Autores principales: Charpentier, Maud, Croyal, Mikael, Carbonnelle, Delphine, Fortun, Agnès, Florenceau, Laetitia, Rabu, Catherine, Krempf, Michel, Labarrière, Nathalie, Lang, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312342/
https://www.ncbi.nlm.nih.gov/pubmed/27486971
http://dx.doi.org/10.18632/oncotarget.10923

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