Cargando…

MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells

Recent reports demonstrate that the expression of protein kinase C alpha (PKCα) in triple-negative breast cancer (TNBC) correlates with decreased survival outcomes. However, off-target effects of targeting PKCα and limited understanding of the signaling mechanisms upstream of PKCα have hampered prev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Chia-Jen, Hsu, Li-Sung, Yue, Chia-Herng, Lin, Ho, Chiu, Yung-Wei, Lin, Yu-Yu, Huang, Chih-Yang, Hung, Mien-Chie, Liu, Jer-Yuh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312353/ https://www.ncbi.nlm.nih.gov/pubmed/27542222 http://dx.doi.org/10.18632/oncotarget.11337

Ejemplares similares

MZF-1/Elk-1 Complex Binds to Protein Kinase Cα Promoter and Is Involved in Hepatocellular Carcinoma
por: Yue, Chia-Herng, et al.
Publicado: (2015)

Correction: MZF-1/Elk-1 Complex Binds to Protein Kinase Cα Promoter and Is Involved in Hepatocellular Carcinoma
por: Yue, Chia-Herng, et al.
Publicado: (2015)

MZF-1/Elk-1/PKCα is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma
por: Ye, Je-Chiuan, et al.
Publicado: (2017)

The Mutational Landscape of the Oncogenic MZF1 SCAN Domain in Cancer
por: Nygaard, Mads, et al.
Publicado: (2016)

Inhibition of MZF1/c-MYC Axis by Cantharidin Impairs Cell Proliferation in Glioblastoma
por: Wang, Chie-Hong, et al.
Publicado: (2022)

Therapeutic targeting of YY1/MZF1 axis by MZF1-uPEP inhibits aerobic glycolysis and neuroblastoma progression
por: Fang, Erhu, et al.
Publicado: (2020)

hMZF-2, the Elusive Transcription Factor
por: Chebly, Alain, et al.
Publicado: (2020)

Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer
por: Qiu, Yufan, et al.
Publicado: (2021)

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A
por: Chao, Ting-Ting, et al.
Publicado: (2014)

Design and In Silico Validation of a Novel MZF-1-Based Multi-Epitope Vaccine to Combat Metastatic Triple Negative Breast Cancer
por: Krishnamoorthy, HemaNandini Rajendran, et al.
Publicado: (2023)

p55PIK Transcriptionally Activated by MZF1 Promotes Colorectal Cancer Cell Proliferation
por: Deng, Yu, et al.
Publicado: (2013)

MZF1 and SCAND1 Reciprocally Regulate CDC37 Gene Expression in Prostate Cancer
por: Eguchi, Takanori, et al.
Publicado: (2019)

Zinc Finger Transcription Factor MZF1—A Specific Regulator of Cancer Invasion
por: Brix, Ditte Marie, et al.
Publicado: (2020)

The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice
por: Wang, Yung-Li, et al.
Publicado: (2021)

EZH2/hSULF1 axis mediates receptor tyrosine kinase signaling to shape cartilage tumor progression
por: Lin, Zong-Shin, et al.
Publicado: (2023)

The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK(+) T-cell lymphoma
por: Vishwamitra, Deeksha, et al.
Publicado: (2015)

MZF1 in the Dorsal Root Ganglia Contributes to the Development and Maintenance of Neuropathic Pain via Regulation of TRPV1
por: Xing, Fei, et al.
Publicado: (2019)

Molecular dynamics simulations and in silico peptide ligand screening of the Elk-1 ETS domain
por: Hussain, Abrar, et al.
Publicado: (2011)

Up-Regulation of FOXM1 by E6 Oncoprotein through the MZF1/NKX2-1 Axis Is Required for Human Papillomavirus–Associated Tumorigenesis()()
por: Chen, Po-Ming, et al.
Publicado: (2014)

MZF1 mediates oncogene-induced senescence by promoting the transcription of p16(INK4A)
por: Wu, Dan, et al.
Publicado: (2022)

Alternatively spliced isoforms of the human elk-1 mRNA within the 5′ UTR: implications for ELK-1 expression
por: Araud, Tanguy, et al.
Publicado: (2007)

HPV-18 E7 Interacts with Elk-1 Leading to Elevation of the Transcriptional Activity of Elk-1 in Cervical Cancer
por: Go, Sung-Ho, et al.
Publicado: (2022)

Therapeutic Targeting of MZF1‐AS1/PARP1/E2F1 Axis Inhibits Proline Synthesis and Neuroblastoma Progression
por: Fang, Erhu, et al.
Publicado: (2019)

Mechanical strain promotes skin fibrosis through LRG-1 induction mediated by ELK1 and ERK signalling
por: Gao, Ya, et al.
Publicado: (2019)

ELKS1 helps neuronal synapses diversify
por: Short, Ben
Publicado: (2017)

Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro
Publicado: (1991)

Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1
por: Cheng, Fong-Yu, et al.
Publicado: (2019)

Egr1/HSP70 Promoter-Driven Activation of Gene Expression for Synergistic Anti-Hepatoma Using PEI-MZF Nanoparticles and Radiation
por: Zhang, Jia, et al.
Publicado: (2022)

Microelimination of Chronic Hepatitis C by Universal Screening Plus Direct-Acting Antivirals for Incarcerated Persons in Taiwan
por: Yang, Tsung-Hua, et al.
Publicado: (2020)

Myeloid Zinc Finger 1 (Mzf1) Differentially Modulates Murine Cardiogenesis by Interacting with an Nkx2.5 Cardiac Enhancer
por: Doppler, Stefanie A., et al.
Publicado: (2014)

Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression
por: Lin, Ching-Chan, et al.
Publicado: (2020)

Current Strategies in Assessment of Nanotoxicity: Alternatives to In Vivo Animal Testing
por: Huang, Hung-Jin, et al.
Publicado: (2021)

Activation of phagocytosis by immune checkpoint blockade
por: Li, Chia-Wei, et al.
Publicado: (2018)

Kinase GSK3β functions as a suppressor in colorectal carcinoma through the FTO‐mediated MZF1/c‐Myc axis
por: Zhang, Zeyan, et al.
Publicado: (2021)

C-Terminal Redox Domain of Arabidopsis APR1 Is a Non-Canonical Thioredoxin Domain with Glutaredoxin Function
por: Chen, Fang-Fang, et al.
Publicado: (2019)

Overlapping promoter targeting by Elk-1 and other divergent ETS-domain transcription factor family members
por: Boros, Joanna, et al.
Publicado: (2009)

Gating and regulation of KCNH (ERG, EAG, and ELK) channels by intracellular domains
por: Codding, Sara J., et al.
Publicado: (2020)

SENP1 participates in the dynamic regulation of Elk-1 SUMOylation
por: Witty, James, et al.
Publicado: (2010)

Osteopontin Mediates an MZF1-TGF-β1-Dependent Transformation of Mesenchymal Stem Cells into Cancer Associated Fibroblasts in Breast Cancer
por: Weber, Cynthia E., et al.
Publicado: (2014)

The role of hypoxia-inducible factor-1α in zinc oxide nanoparticle-induced nephrotoxicity in vitro and in vivo
por: Lin, Yuh-Feng, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4g7ogfav7ui6sipqf9hhv2g3fv