The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA

Alterations in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells. Here, we identify the host transcript of miR-223, linc-223, as a novel functional long non-coding RNA (lncRNA) in AML. We show that from the prima...

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Detalles Bibliográficos
Autores principales: Mangiavacchi, Arianna, Sorci, Melissa, Masciarelli, Silvia, Larivera, Simone, Legnini, Ivano, Iosue, Ilaria, Bozzoni, Irene, Fazi, Francesco, Fatica, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312375/
https://www.ncbi.nlm.nih.gov/pubmed/27517498
http://dx.doi.org/10.18632/oncotarget.11165

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