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Mild electrical stimulation with heat shock guides differentiation of embryonic stem cells into Pdx1-expressing cells within the definitive endoderm

BACKGROUND: Because of the increasing number of diabetic patients, it is important to generate pancreatic and duodenal homeobox gene 1 (Pdx1)-expressing cells, which are capable of differentiating into pancreatic endocrine β cells. Mild electrical stimulation was reported to modulate the differentia...

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Detalles Bibliográficos
Autores principales:	Koga, Tomoaki, Shiraki, Nobuaki, Yano, Shuichiro, Suico, Mary Ann, Morino-Koga, Saori, Sato, Takashi, Shuto, Tsuyoshi, Kume, Shoen, Kai, Hirofumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312430/ https://www.ncbi.nlm.nih.gov/pubmed/28202025 http://dx.doi.org/10.1186/s12896-017-0331-z

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