Clinical performance evaluation of a sensitive, rapid low-throughput test for KRAS mutation analysis using formalin-fixed, paraffin-embedded tissue samples

BACKGROUND: Testing for KRAS mutations in metastatic colorectal cancer (mCRC) on formalin-fixed, paraffin embedded (FFPE) tumor tissue has become standard of care. Different molecular methods exist to determine hotspot KRAS mutations in exon 2, 3 and 4, but testing is often limited by the sensitivit...

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Detalles Bibliográficos
Autores principales: Weyn, Christine, Van Raemdonck, Sofie, Dendooven, Robina, Maes, Vincent, Zwaenepoel, Karen, Lambin, Suzan, Pauwels, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312443/
https://www.ncbi.nlm.nih.gov/pubmed/28201998
http://dx.doi.org/10.1186/s12885-017-3112-0

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