Cargando…
A vast genomic deletion in the C56BL/6 genome affects different genes within the Ifi200 cluster on chromosome 1 and mediates obesity and insulin resistance
BACKGROUND: Obesity, the excessive accumulation of body fat, is a highly heritable and genetically heterogeneous disorder. The complex, polygenic basis for the disease consisting of a network of different gene variants is still not completely known. RESULTS: In the current study we generated a BAC l...
Autores principales: | Vogel, Heike, Jähnert, Markus, Stadion, Mandy, Matzke, Daniela, Scherneck, Stephan, Schürmann, Annette |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312539/ https://www.ncbi.nlm.nih.gov/pubmed/28201990 http://dx.doi.org/10.1186/s12864-017-3552-6 |
Ejemplares similares
-
Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans
por: Stadion, Mandy, et al.
Publicado: (2018) -
Distinct Adipogenic and Fibrogenic Differentiation Capacities of Mesenchymal Stromal Cells from Pancreas and White Adipose Tissue
por: Aga, Heja, et al.
Publicado: (2022) -
The diabetes gene Zfp69 modulates hepatic insulin sensitivity in mice
por: Chung, Bomee, et al.
Publicado: (2015) -
Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation
por: Kluth, Oliver, et al.
Publicado: (2015) -
An Interval of the Obesity QTL Nob3.38 within a QTL Hotspot on Chromosome 1 Modulates Behavioral Phenotypes
por: Vogel, Heike, et al.
Publicado: (2013)